The 'VDIManagerUsers' setting should be informed when there are multiple domains.
The "VDIManagerUsers” setting must contain the name of an Active Directory group. The SUITE will add and remove to this group the users that have access to the SUITE.
This group is configured in the Web VCC roles as explained in Web VCC role requirements to improve performance when those users belong to more than one domain.
In multiple domains environments if this setting is not configured there may be performance problems when browsing the SUITE.